The following tests are available from Nutrisearch. RGCC is a European laboratory.

 Test

Purpose

 Cost

Oncocount Circulating tumour cell count  $950
Oncotrace Circulating tumour cell count and their origin (immunophenotype) $1200
Oncotrail Level and type of circulating tumour cells in case of specific cancers $1100
Onconomics CTC quantity and immunophenotyping, Radiotherapy/Hyperthermia sensitivity,
Chemosensitivity/Chemoresistance of cytotoxic drugs, targeted therapies
$2700
Onconomics Extracts CTC quantity and chemosensitivity of natural substances and plant extracts  $2300
Onconomics Plus CTC quantity and immunophenotyping, Radiotherapy/Hyperthermia sensitivity.
Chemosensitivity/Chemoresistance of cytotoxic drugs, targeted therapies AND
natural substances and plant extracts
 $3200
Cambiseq Helps predict the response to immuno therapy  $
Metastat Helps predict likelyhood of the cancer to spread to other sites  $1200
ChemoSNiP Inherited gene variations (SNPs). Helps predicting response to drugs  $1400
ImmuneFrame Profile for assessing the status of the immune system, in particular the
humoral and cellular immunity systems and incidence of cachexia
$1200

Oncocount RGCC

This test detects the presence of circulating tumour cells, and measures their concentration in the blood. As these cells that could lead to the recurrence of a cancer, this test is useful to detect relapse early, and as a follow-up tool.

  • Cost: $950

Oncotrace RGCC

This test provides information about the presence of circulating tumour cells, and their concentration and immunophenotype, which may help identify their origin. It is used to provide guidance about a patient’s prognosis, and to help identify the primary tumour when this is unknown.

  •  Cost: $1200

Oncotrail RGCC

This test provides information about the presence of circulating tumour cells, their concentration, and immunophenotype for specific types of malignancies. This test is a tailor-made test for certain cancers: such as breast cancer (for which we provide the Oncotrail RGCC for breast cancer) and prostate cancer (for which we provide Oncotrail RGCC for prostate cancer. The Oncotrail RGCC test only includes the relevant markers for a specific malignancy, making it suitable tool for follow up.

  • Cost: $1100

 Onconomics Extracts

This test provides information about the efficacy of natural biological substances or extracts on circulating tumour cells. Onconomics Extracts focuses on testing using three methods: testing for the direct effect of an anti-cancer treatment, stimulating the immune system and inhibiting proliferative signals in the cancer cells that stimulate them to grow.

  • Cost: $2300

Onconomics Plus RGCC

This test provides information about the effect of specific anti-cancer drugs, targeted therapies and natural treatments on the cancer cells in an individual patient. The test combines a molecular and a cellular approach by incorporating two procedures: epigenetic analysis and viability assays.

Onconomics Plus RGCC is based on three methods: testing for the direct effect of an anti-cancer treatment, stimulating the immune system and inhibiting proliferative signals in the cancer cells that stimulate them to grow.

  • Cost: $3200

 RGCC CAMBISeq™

RGCC CAMBISeq (cancer analysis, mutational burden and instability sequencing) provides next generation sequencing analysis on both DNA and RNA to help predict a patient’s response to immunotherapy and to detect variants.

Array comparative genomic hybridisation (aCGH) RGCC

This test identifies chromosomal abnormalities – when either part of the genetic sequence in a chromosome is deleted or added to – that might lead to cancer. It uses a technique called array CGH to identify abnormalities in a genome more clearly than traditional microscopes can. These abnormalities could be linked with parts of regions that might be useful to identify the origin of a primary tumour.
Purpose of the test

This test focuses on the status of a patient’s immune system. The test uses specific cellular markers, and the production of proteins called cytokines, to detect the type or types of cells that are responsible for switching a patient’s immune system on and off.

Immune-Frame uses two different assays: the ELISA assay is used to detect cytokines produced by specific cells, and flow cytometry is used to measure specific markers on blood cells in the peripheral vascular system.

  • Cost: $

 Metastat RGCC

This test provides information, based on the detection of circulating tumour cells, about whether and where the tumour is likely to spread.

Studies show that the cancer cells that have the potential to spread from the primary tumour express specific genes and proteins, or markers. These markers vary according to the organ that the tumour will spread to.

The Metastat test looks for a collection of markers that are detected on specific organs and parts of the body, such as the lung, brain, liver, and bones.

  • Cost: $1200

 ChemoSNiP

This test relies on pharmacogenomics. This is the science of inherited variations in genes, how these inherited variations dictate a patient’s response to a drug, and the ways these variations can be used to predict whether a patient will have a good or bad response to a drug, or no response at all.

ChemoSNiP tests for single nucleotide polymorphisms – variations in our DNA sequence that can affect if we develop cancer or if we respond to treatments with chemicals, drugs and other agents.

It studies single nucleotide polymorphisms in the genes that are involved in breaking down cytostatic (anti-cancer) or targeted drugs that are used in cancer therapy, and provides information about the ability of each individual to break down and trigger a treatment in the most effective way.

  • Cost: $1400

Immune-Frame

This test focuses on the status of a patient’s immune system. The test uses specific cellular markers, and the production of proteins called cytokines, to detect the type or types of cells that are responsible for switching a patient’s immune system on and off. Immune-Frame uses two different assays: the ELISA assay is used to detect cytokines produced by specific cells, and flow cytometry is used to measure specific markers on blood cells in the peripheral vascular system.

  • Cost: $1200